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1.
When a person decides to tell a love interest that they like them and get rejected, they become so depressed that instead of gaining weight they lose it.
(In honor of this kid who lost so much weight because he got rejected).
Pino: hey, have you noticed that Juan has lost a lot of weight?

Eddy: Oh, you didn't know? he suffered from Lance Syndrome. Some chick rejected him.
作者 Eddykid 2009年2月24日

Words related to Lance Syndrome

crying depression rejection sadness weight loss