To have sex with a dog.
Jize Layo screwed the pooch for his new film, "Jize Layo does a dachsund IV"
作者 Jose Loya 2005年8月14日

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Past tense of making a major mistake
"Man, I really screwed the pooch when I talked to my boss while I was druck last night."
作者 Quentin 2003年7月31日

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Another way of saying "blew it" or "messed up".
"You really screwed the pooch on that one dude".
作者 Barb 2004年9月09日

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The act of really messing things up.
Damn, i really screwed the pooch on that one.
作者 madmanmarx 2007年10月10日

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A way in which to describe a mistake or blunder.
"That computer's a lemon, I really screwed the pooch on that deal!"
作者 c. Wallace 2004年5月21日

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To commit a blatant heinously humiliating error.
When he got drunk and took on the ninja, he really screwed the pooch.
作者 postmachoguy 2009年1月03日

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to screw up
Boy who ever approved the new Big Tex design really screwed the pooch!
作者 screwedthepooch 2013年10月04日

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Screwing the pooch is a nonsensical action that is being done while a major fuck up is occuring or has occured.
Management have screwed the pooch while the competition gained the upperhand.
作者 ANTZILLA 2014年7月13日

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