1. a southern slang phrase that means "flying off the handle", losing ones cool and losing ones self-control. Some people also think it could mean to get laid.
2. a big 1991 hit song from the Georgia rock band R.E.M..
1. George: Jeremy has been acting funny since he polished off a bottle of Wild Turkey.
Billy: Yep, he's lost some of his religion.
2. The title "Losing My Religion" caused some confusion at first here in the MidWest.
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